BPTF Regulates Growth of Adult and Pediatric High-Grade Glioma through the MYC Pathway

High-grade gliomas (HGG) afflict both children and adults and respond poorly to current therapies. Epigenetic regulators have a role in gliomagenesis, but a broad, functional investigation of the impact and role of specific epigenetic targets has not been undertaken. Using a two-step, in vitro/in vi...

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Detalles Bibliográficos
Autores principales: Green, Adam L., DeSisto, John, Flannery, Patrick, Lemma, Rakeb, Knox, Aaron, Lemieux, Madeleine, Sanford, Bridget, O’Rourke, Rebecca, Ramkissoon, Shakti, Jones, Kristen, Perry, Jennifer, Hui, Xu, Moroze, Erin, Balakrishnan, Ilango, O’Neill, Allison F., Dunn, Katherine, DeRyckere, Deborah, Danis, Etienne, Safadi, Aaron, Gilani, Ahmed, Hubbell-Engler, Benjamin, Nuss, Zachary, Mulcahy Levy, Jean M., Serkova, Natalie, Venkataraman, Sujatha, Graham, Douglas K., Foreman, Nicholas, Ligon, Keith, Jones, Ken, Kung, Andrew, Vibhakar, Rajeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071968/
https://www.ncbi.nlm.nih.gov/pubmed/31844250
http://dx.doi.org/10.1038/s41388-019-1125-7

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