CCR2 signaling in breast carcinoma cells promotes tumor growth and invasion by promoting CCL2 and suppressing CD154 effects on the angiogenic and immune microenvironments

Breast cancer is the second leading cause of cancer related deaths for women, due mainly to metastatic disease. Invasive tumors exhibit aberrations in recruitment and activity of immune cells, including decreased cytotoxic T cells. Restoring the levels and activity of cytotoxic T cells is a promisin...

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Detalles Bibliográficos
Autores principales: Brummer, Gage, Fang, Wei, Smart, Curtis, Zinda, Brandon, Alissa, Nadia, Berkland, Cory, Miller, David, Cheng, Nikki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071973/
https://www.ncbi.nlm.nih.gov/pubmed/31827233
http://dx.doi.org/10.1038/s41388-019-1141-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7071973/
https://www.ncbi.nlm.nih.gov/pubmed/31827233
http://dx.doi.org/10.1038/s41388-019-1141-7

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