PARP Inhibitors as Therapeutics: Beyond Modulation of PARylation

Poly (ADP-ribose) polymerase (PARP) 1 is an essential molecule in DNA damage response by sensing DNA damage and docking DNA repair proteins on the damaged DNA site through a type of posttranslational modification, poly (ADP-Ribosyl)ation (PARylation). PARP inhibitors, which inhibit PARylation throug...

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Detalles Bibliográficos
Autores principales: Min, Ahrum, Im, Seock-Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072193/
https://www.ncbi.nlm.nih.gov/pubmed/32046300
http://dx.doi.org/10.3390/cancers12020394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072193/
https://www.ncbi.nlm.nih.gov/pubmed/32046300
http://dx.doi.org/10.3390/cancers12020394

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