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Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis
Non-coding RNA molecules including microRNAs and long non-coding RNAs (lncRNA) have been implicated in the pathogenesis of several tumors and numerous data support their applicability in diagnosis as well. Despite recent advances, the pathogenesis of adrenocortical cancer still remains elusive and t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072220/ https://www.ncbi.nlm.nih.gov/pubmed/32079166 http://dx.doi.org/10.3390/cancers12020461 |
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author | Decmann, Abel Perge, Pál Turai, Peter Istvan Patócs, Attila Igaz, Peter |
author_facet | Decmann, Abel Perge, Pál Turai, Peter Istvan Patócs, Attila Igaz, Peter |
author_sort | Decmann, Abel |
collection | PubMed |
description | Non-coding RNA molecules including microRNAs and long non-coding RNAs (lncRNA) have been implicated in the pathogenesis of several tumors and numerous data support their applicability in diagnosis as well. Despite recent advances, the pathogenesis of adrenocortical cancer still remains elusive and there are no reliable blood-borne markers of adrenocortical malignancy, either. Several findings show the potential applicability of microRNAs as biomarkers of malignancy and prognosis, and there are some data on lncRNA as well. In this review, we present a synopsis on the potential relevance of non-coding RNA molecules in adrenocortical pathogenesis and their applicability in diagnosis from tissue and blood. |
format | Online Article Text |
id | pubmed-7072220 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-70722202020-03-19 Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis Decmann, Abel Perge, Pál Turai, Peter Istvan Patócs, Attila Igaz, Peter Cancers (Basel) Review Non-coding RNA molecules including microRNAs and long non-coding RNAs (lncRNA) have been implicated in the pathogenesis of several tumors and numerous data support their applicability in diagnosis as well. Despite recent advances, the pathogenesis of adrenocortical cancer still remains elusive and there are no reliable blood-borne markers of adrenocortical malignancy, either. Several findings show the potential applicability of microRNAs as biomarkers of malignancy and prognosis, and there are some data on lncRNA as well. In this review, we present a synopsis on the potential relevance of non-coding RNA molecules in adrenocortical pathogenesis and their applicability in diagnosis from tissue and blood. MDPI 2020-02-17 /pmc/articles/PMC7072220/ /pubmed/32079166 http://dx.doi.org/10.3390/cancers12020461 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Decmann, Abel Perge, Pál Turai, Peter Istvan Patócs, Attila Igaz, Peter Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis |
title | Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis |
title_full | Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis |
title_fullStr | Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis |
title_full_unstemmed | Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis |
title_short | Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis |
title_sort | non-coding rnas in adrenocortical cancer: from pathogenesis to diagnosis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072220/ https://www.ncbi.nlm.nih.gov/pubmed/32079166 http://dx.doi.org/10.3390/cancers12020461 |
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