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Prognosis, Biology, and Targeting of TP53 Dysregulation in Multiple Myeloma
Multiple myeloma (MM) is the second most common hematological cancer and is characterized by genetic features including translocations, chromosomal copy number aberrations, and mutations in key oncogene and tumor suppressor genes. Dysregulation of the tumor suppressor TP53 is important in the pathog...
Autores principales: | Flynt, Erin, Bisht, Kamlesh, Sridharan, Vinidhra, Ortiz, María, Towfic, Fadi, Thakurta, Anjan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072230/ https://www.ncbi.nlm.nih.gov/pubmed/31991614 http://dx.doi.org/10.3390/cells9020287 |
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