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Astrocyte Infection during Rabies Encephalitis Depends on the Virus Strain and Infection Route as Demonstrated by Novel Quantitative 3D Analysis of Cell Tropism

Although conventional immunohistochemistry for neurotropic rabies virus (RABV) usually shows high preference for neurons, non-neuronal cells are also potential targets, and abortive astrocyte infection is considered a main trigger of innate immunity in the CNS. While in vitro studies indicated diffe...

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Detalles Bibliográficos
Autores principales: Potratz, Madlin, Zaeck, Luca, Christen, Michael, te Kamp, Verena, Klein, Antonia, Nolden, Tobias, Freuling, Conrad M., Müller, Thomas, Finke, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072253/
https://www.ncbi.nlm.nih.gov/pubmed/32053954
http://dx.doi.org/10.3390/cells9020412