The RNA-Binding Ubiquitin Ligase MEX3A Affects Glioblastoma Tumorigenesis by Inducing Ubiquitylation and Degradation of RIG-I

Glioblastoma multiforme (GB) is the most malignant primary brain tumor in humans, with an overall survival of approximatively 15 months. The molecular heterogeneity of GB, as well as its rapid progression, invasiveness and the occurrence of drug-resistant cancer stem cells, limits the efficacy of th...

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Detalles Bibliográficos
Autores principales: Bufalieri, Francesca, Caimano, Miriam, Lospinoso Severini, Ludovica, Basili, Irene, Paglia, Francesco, Sampirisi, Luigi, Loricchio, Elena, Petroni, Marialaura, Canettieri, Gianluca, Santoro, Antonio, D’Angelo, Luca, Infante, Paola, Di Marcotullio, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072305/
https://www.ncbi.nlm.nih.gov/pubmed/32019099
http://dx.doi.org/10.3390/cancers12020321

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