Cargando…
Bezafibrate Improves Mitochondrial Fission and Function in DNM1L-Deficient Patient Cells
Mitochondria are involved in many cellular processes and their main role is cellular energy production. They constantly undergo fission and fusion, and these counteracting processes are under strict balance. The cytosolic dynamin-related protein 1, Drp1, or dynamin-1-like protein (DNM1L) mediates mi...
Autores principales: | Douiev, Liza, Sheffer, Ruth, Horvath, Gabriella, Saada, Ann |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072316/ https://www.ncbi.nlm.nih.gov/pubmed/32012656 http://dx.doi.org/10.3390/cells9020301 |
Ejemplares similares
-
Loss-of-function variants in DNM1 cause a specific form of developmental and epileptic encephalopathy only in biallelic state
por: Yigit, Gökhan, et al.
Publicado: (2022) -
A Mutation in the Mitochondrial Fission Gene Dnm1l Leads to Cardiomyopathy
por: Ashrafian, Houman, et al.
Publicado: (2010) -
De novo pathogenic DNM1L variant in a patient diagnosed with atypical hereditary sensory and autonomic neuropathy
por: Tarailo‐Graovac, Maja, et al.
Publicado: (2019) -
Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission
por: Mears, Jason A., et al.
Publicado: (2010) -
BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma
por: Wang, Jiwei, et al.
Publicado: (2023)