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WNT5a-ROR Signaling Is Essential for Alveologenesis
WNT5a is a mainly “non-canonical” WNT ligand whose dysregulation is observed in lung diseases such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and asthma. Germline deletion of Wnt5a disrupts embryonic lung development. However, the temporal-specific function...
Autores principales: | Li, Changgong, Smith, Susan M, Peinado, Neil, Gao, Feng, Li, Wei, Lee, Matt K, Zhou, Beiyun, Bellusci, Saverio, Pryhuber, Gloria S, Ho, Hsin-Yi Henry, Borok, Zea, Minoo, Parviz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072327/ https://www.ncbi.nlm.nih.gov/pubmed/32046118 http://dx.doi.org/10.3390/cells9020384 |
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