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Discovery of Kynurenines Containing Oligopeptides as Potent Opioid Receptor Agonists
Kynurenine (kyn) and kynurenic acid (kyna) are well-defined metabolites of tryptophan catabolism collectively known as “kynurenines”, which exert regulatory functions in host-microbiome signaling, immune cell response, and neuronal excitability. Kynurenine containing peptides endowed with opioid rec...
Autores principales: | Szűcs, Edina, Stefanucci, Azzurra, Dimmito, Marilisa Pia, Zádor, Ferenc, Pieretti, Stefano, Zengin, Gokhan, Vécsei, László, Benyhe, Sándor, Nalli, Marianna, Mollica, Adriano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072329/ https://www.ncbi.nlm.nih.gov/pubmed/32059524 http://dx.doi.org/10.3390/biom10020284 |
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