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Obesity Promotes Cooperation of Cancer Stem-Like Cells and Macrophages to Enhance Mammary Tumor Angiogenesis
Obesity is correlated with worsened prognosis and treatment resistance in breast cancer. Macrophage-targeted therapies are currently in clinical trials, however, little is known about how obesity may impact treatment efficacy. Within breast adipose tissue, obesity leads to chronic, macrophage-driven...
Autores principales: | Hillers-Ziemer, Lauren E., McMahon, Rachel Q., Hietpas, Margaret, Paderta, Gretchen, LeBeau, Jennelle, McCready, Jessica, Arendt, Lisa M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072330/ https://www.ncbi.nlm.nih.gov/pubmed/32098183 http://dx.doi.org/10.3390/cancers12020502 |
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