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Intratumoral Genetic Heterogeneity in Papillary Thyroid Cancer: Occurrence and Clinical Significance

Intratumoral heterogeneity (ITH) refers to a subclonal genetic diversity observed within a tumor. ITH is the consequence of genetic instability and accumulation of genetic alterations, two mechanisms involved in the progression from an early tumor stage to a more aggressive cancer. While this proces...

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Detalles Bibliográficos
Autores principales:	Fugazzola, Laura, Muzza, Marina, Pogliaghi, Gabriele, Vitale, Mario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072350/ https://www.ncbi.nlm.nih.gov/pubmed/32046148 http://dx.doi.org/10.3390/cancers12020383

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