Synthetic 4-Hydroxy Auxarconjugatin B, a Novel Autophagy Inducer, Attenuates Gouty Inflammation by Inhibiting the NLRP3 Inflammasome

Gouty arthritis results from the generation of uric acid crystals within the joints. These uric acid crystals activate the NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome, which is involved in chronic inflammatory diseases, including gouty arthritis. This study identified the po...

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Detalles Bibliográficos
Autores principales: Hsieh, Chih-Yu, Li, Lan-Hui, Lam, Yulin, Fang, Zhanxiong, Gan, Chin Heng, Rao, Yerra Koteswara, Chiu, Hsiao-Wen, Wong, Wei-Ting, Ju, Tz-Chuen, Chen, Fang-Hsin, Chernikov, Oleg V., Liu, May-Lan, Hsu, Chung-Hua, Hua, Kuo-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072356/
https://www.ncbi.nlm.nih.gov/pubmed/31979265
http://dx.doi.org/10.3390/cells9020279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072356/
https://www.ncbi.nlm.nih.gov/pubmed/31979265
http://dx.doi.org/10.3390/cells9020279

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