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Synthetic 4-Hydroxy Auxarconjugatin B, a Novel Autophagy Inducer, Attenuates Gouty Inflammation by Inhibiting the NLRP3 Inflammasome
Gouty arthritis results from the generation of uric acid crystals within the joints. These uric acid crystals activate the NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome, which is involved in chronic inflammatory diseases, including gouty arthritis. This study identified the po...
Autores principales: | Hsieh, Chih-Yu, Li, Lan-Hui, Lam, Yulin, Fang, Zhanxiong, Gan, Chin Heng, Rao, Yerra Koteswara, Chiu, Hsiao-Wen, Wong, Wei-Ting, Ju, Tz-Chuen, Chen, Fang-Hsin, Chernikov, Oleg V., Liu, May-Lan, Hsu, Chung-Hua, Hua, Kuo-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072356/ https://www.ncbi.nlm.nih.gov/pubmed/31979265 http://dx.doi.org/10.3390/cells9020279 |
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