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Antiparkinson Drug Benztropine Suppresses Tumor Growth, Circulating Tumor Cells, and Metastasis by Acting on SLC6A3/DAT and Reducing STAT3

Tumor growth, progression, and therapy resistance are crucial factors in the prognosis of cancer. The properties of three-dimensional (3D) tumor-like organoids (tumoroids) more closely resemble in vivo tumors compared to two-dimensionally cultured cells and are therefore effectively used for assays...

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Detalles Bibliográficos
Autores principales:	Sogawa, Chiharu, Eguchi, Takanori, Tran, Manh Tien, Ishige, Masayuki, Trin, Kilian, Okusha, Yuka, Taha, Eman Ahmed, Lu, Yanyin, Kawai, Hotaka, Sogawa, Norio, Takigawa, Masaharu, Calderwood, Stuart K., Okamoto, Kuniaki, Kozaki, Ken-ichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072357/ https://www.ncbi.nlm.nih.gov/pubmed/32102440 http://dx.doi.org/10.3390/cancers12020523

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