Cargando…

Investigation of α-Glucosidase Inhibitory Metabolites from Tetracera scandens Leaves by GC–MS Metabolite Profiling and Docking Studies

Stone leaf (Tetracera scandens) is a Southeast Asian medicinal plant that has been traditionally used for the management of diabetes mellitus. The underlying mechanisms of the antidiabetic activity have not been fully explored yet. Hence, this study aimed to evaluate the α-glucosidase inhibitory pot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nokhala, Ahmed, Siddiqui, Mohammad Jamshed, Ahmed, Qamar Uddin, Ahamad Bustamam, Muhammad Safwan, Zakaria, Zainul Amiruddin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072363/ https://www.ncbi.nlm.nih.gov/pubmed/32059529 http://dx.doi.org/10.3390/biom10020287

Ejemplares similares

Phytochemicals and biological activity of Tetracera scandens Linn. Merr. (Dilleniaceae): A short review
por: Nokhala, Ahmed, et al.
Publicado: (2020)

Flavonoids from Tetracera indica Merr. induce adipogenesis and exert glucose uptake activities in 3T3-L1 adipocyte cells
por: Hasan, Md. Mahmudul, et al.
Publicado: (2017)

An In Vitro Anticancer Activity Evaluation of Neolamarckia cadamba (Roxb.) Bosser Leaves’ Extract and its Metabolite Profile
por: Razali, Shakirah, et al.
Publicado: (2021)

Identification of Antidiabetic Metabolites from Paederia foetida L. Twigs by Gas Chromatography-Mass Spectrometry-Based Metabolomics and Molecular Docking Study
por: Tan, Dai Chuan, et al.
Publicado: (2019)

Comprehensive GCMS and LC-MS/MS Metabolite Profiling of Chlorella vulgaris
por: Pantami, Hamza Ahmed, et al.
Publicado: (2020)

Synthesis of new isoquinoline-base-oxadiazole derivatives as potent inhibitors of thymidine phosphorylase and molecular docking study
por: Zaman, Khalid, et al.
Publicado: (2019)

GC-MS- and NMR-Based Metabolomics and Molecular Docking Reveal the Potential Alpha-Glucosidase Inhibitors from Psychotria malayana Jack Leaves
por: Nipun, Tanzina Sharmin, et al.
Publicado: (2021)

Pseudocedrela kotschyi: a review of ethnomedicinal uses, pharmacology and phytochemistry
por: Alhassan, Alhassan M., et al.
Publicado: (2021)

Complementary Analytical Platforms of NMR Spectroscopy and LCMS Analysis in the Metabolite Profiling of Isochrysis galbana
por: Bustamam, Muhammad Safwan Ahamad, et al.
Publicado: (2021)

In Vitro, In Silico and Network Pharmacology Mechanistic Approach to Investigate the α-Glucosidase Inhibitors Identified by Q-ToF-LCMS from Phaleria macrocarpa Fruit Subcritical CO(2) Extract
por: Mia, Md. Abdur Rashid, et al.
Publicado: (2022)

Metabolite Profiling of the Microalgal Diatom Chaetoceros Calcitrans and Correlation with Antioxidant and Nitric Oxide Inhibitory Activities via (1)H NMR-Based Metabolomics
por: Azizan, Awanis, et al.
Publicado: (2018)

Synthesis of Thymidine Phosphorylase Inhibitor Based on Quinoxaline Derivatives and Their Molecular Docking Study
por: Almandil, Noor Barak, et al.
Publicado: (2019)

Facile Synthesis of Functionalized Phenoxy Quinolines: Antibacterial Activities against ESBL Producing Escherichia coli and MRSA, Docking Studies, and Structural Features Determination through Computational Approach
por: Arshad, Mahwish, et al.
Publicado: (2022)

α-Glucosidase Inhibition and Molecular Docking Studies of Natural Brominated Metabolites from Marine Macro Brown Alga Dictyopteris hoytii
por: Ur Rehman, Najeeb, et al.
Publicado: (2019)

Antimicrobial Secondary Metabolites from the Mangrove Plants of Asia and the Pacific
por: Sulaiman, Mazdida, et al.
Publicado: (2022)

Metabolite Profiles of Red and Yellow Watermelon (Citrullus lanatus) Cultivars Using a (1)H-NMR Metabolomics Approach
por: Sulaiman, Fadzil, et al.
Publicado: (2020)

Evaluation and Comparison of Trachyspermum ammi Seed Extract for Its Anti-inflammatory Effect
por: Aslam, Adeel, et al.
Publicado: (2020)

Antinociceptive activity of petroleum ether fraction obtained from methanolic extract of Clinacanthus nutans leaves involves the activation of opioid receptors and NO-mediated/cGMP-independent pathway
por: Zakaria, Zainul Amiruddin, et al.
Publicado: (2019)

Exploring Novel Pyridine Carboxamide Derivatives as Urease Inhibitors: Synthesis, Molecular Docking, Kinetic Studies and ADME Profile
por: Naseer, Ayesha, et al.
Publicado: (2022)

Characterization of α-Glucosidase Inhibitors from Clinacanthus nutans Lindau Leaves by Gas Chromatography-Mass Spectrometry-Based Metabolomics and Molecular Docking Simulation
por: Murugesu, Suganya, et al.
Publicado: (2018)

Evaluation of the Enzyme Inhibitory and Antioxidant Activities of Entada spiralis Stem Bark and Isolation of the Active Constituents
por: Roheem, Fatimah Opeyemi, et al.
Publicado: (2019)

Cardioprotective effects of arjunolic acid in LPS-stimulated H9C2 and C2C12 myotubes via the My88-dependent TLR4 signaling pathway
por: Hasan, Md Mahmudul, et al.
Publicado: (2023)

Characterization of α-Glucosidase Inhibitors from Psychotria malayana Jack Leaves Extract Using LC-MS-Based Multivariate Data Analysis and In-Silico Molecular Docking
por: Nipun, Tanzina Sharmin, et al.
Publicado: (2020)

Effect of storage time on metabolite profile and alpha-glucosidase inhibitory activity of Cosmos caudatus leaves – GCMS based metabolomics approach
por: Javadi, Neda, et al.
Publicado: (2015)

Synthesis of Benzimidazole–Based Analogs as Anti Alzheimer’s Disease Compounds and Their Molecular Docking Studies
por: Adalat, Bushra, et al.
Publicado: (2020)

Evaluation of acute toxicity and intestinal transit time of Olax scandens Roxb. leaves
por: Naik, Raghavendra, et al.
Publicado: (2015)

GC-MS Based Metabolite Profiling to Monitor Ripening-Specific Metabolites in Pineapple (Ananas comosus)
por: Ikram, Muhammad Maulana Malikul, et al.
Publicado: (2020)

Feruloylmonotropeins: promising natural antioxidants in Paederia scandens
por: Trung, Nguyen Quang, et al.
Publicado: (2023)

Antimicrobial, antiproliferative activities and molecular docking of metabolites from Alternaria alternata
por: Khazaal, Heba T., et al.
Publicado: (2023)

Deciphering the antimicrobial, antibiofilm and membrane stabilizing synergism of Mikania scandens (L.) Willd. leaves and stems substantiation through in vitro and in silico studies
por: Tumpa, Nadia Islam, et al.
Publicado: (2023)

Antibacterial Effects of Flavonoids and Their Structure-Activity Relationship Study: A Comparative Interpretation
por: Shamsudin, Nur Farisya, et al.
Publicado: (2022)

Identifying and quantifying metabolites by scoring peaks of GC-MS data
por: Aggio, Raphael BM, et al.
Publicado: (2014)

GC-MS profiling of volatile metabolites produced by Klebsiella pneumoniae
por: Filipiak, Wojciech, et al.
Publicado: (2022)

Metabolites of Geum aleppicum and Sibbaldianthe bifurca: Diversity and α-Glucosidase Inhibitory Potential
por: Kashchenko, Nina I., et al.
Publicado: (2023)

Neuropharmacological properties of Mikania scandens (L.) Willd. (Asteraceae)
por: Dey, Protapaditya, et al.
Publicado: (2011)

Complete chloroplast genome sequence of Ampelocalamus scandens (Arundinarodae)
por: Fan, Lili, et al.
Publicado: (2020)

Identification of highly potent α-glucosidase inhibitory and antioxidant constituents from Zizyphus rugosa bark: enzyme kinetic and molecular docking studies with active metabolites
por: Sichaem, Jirapast, et al.
Publicado: (2017)

The In Vitro α-Glucosidase Inhibition Activity of Various Solvent Fractions of Tamarix dioica and (1)H-NMR Based Metabolite Identification and Molecular Docking Analysis
por: Niaz, Aamir, et al.
Publicado: (2021)

α-Mangostin Improves Glucose Uptake and Inhibits Adipocytes Differentiation in 3T3-L1 Cells via PPARγ, GLUT4, and Leptin Expressions
por: Taher, Muhammad, et al.
Publicado: (2015)

Evaluation of Phytochemical Screening and Anti Inflammatory Activity of Leaves and Stem of Mikania scandens (L.) Wild
por: Banerjee, S, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_nnrjiebf5qrqp9slrnqadl71hp