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Protein Tyrosine Phosphatase-1B Inhibition Disrupts IL13Rα2-Promoted Invasion and Metastasis in Cancer Cells
Background: Interleukin 13 receptor alpha 2 subunit (IL13Rα2) is overexpressed in glioblastoma (GBM), metastatic colorectal cancer (CRC) and ovarian cancer (OC). Here, we investigated the IL13Rα2 interactome searching for novel targets in cancer invasion and metastasis. Methods: The interactome of I...
Autores principales: | Bartolomé, Rubén A., Martín-Regalado, Ángela, Jaén, Marta, Zannikou, Markella, Zhang, Peng, de los Ríos, Vivian, Balyasnikova, Irina V., Casal, J. Ignacio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072372/ https://www.ncbi.nlm.nih.gov/pubmed/32098194 http://dx.doi.org/10.3390/cancers12020500 |
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