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Protein Tyrosine Phosphatase-1B Inhibition Disrupts IL13Rα2-Promoted Invasion and Metastasis in Cancer Cells

Background: Interleukin 13 receptor alpha 2 subunit (IL13Rα2) is overexpressed in glioblastoma (GBM), metastatic colorectal cancer (CRC) and ovarian cancer (OC). Here, we investigated the IL13Rα2 interactome searching for novel targets in cancer invasion and metastasis. Methods: The interactome of I...

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Detalles Bibliográficos
Autores principales: Bartolomé, Rubén A., Martín-Regalado, Ángela, Jaén, Marta, Zannikou, Markella, Zhang, Peng, de los Ríos, Vivian, Balyasnikova, Irina V., Casal, J. Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072372/
https://www.ncbi.nlm.nih.gov/pubmed/32098194
http://dx.doi.org/10.3390/cancers12020500

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