Metabolism of Estrogens: Turnover Differs between Platinum-Sensitive and -Resistant High-Grade Serous Ovarian Cancer Cells

High-grade serous ovarian cancer (HGSOC) is currently treated with cytoreductive surgery and platinum-based chemotherapy. The majority of patients show a primary response; however, many rapidly develop drug resistance. Antiestrogens have been studied as low toxic treatment options for HGSOC, with hi...

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Detalles Bibliográficos
Autores principales: Poschner, Stefan, Wackerlig, Judith, Castillo-Tong, Dan Cacsire, Wolf, Andrea, von der Decken, Isabel, Rižner, Tea Lanišnik, Pavlič, Renata, Meshcheryakova, Anastasia, Mechtcheriakova, Diana, Fritzer-Szekeres, Monika, Thalhammer, Theresia, Jäger, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072378/
https://www.ncbi.nlm.nih.gov/pubmed/31979221
http://dx.doi.org/10.3390/cancers12020279

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