Cargando…
Alternative Mechanisms of p53 Action During the Unfolded Protein Response
The tumor suppressor protein p53 orchestrates cellular responses to a vast number of stresses, with DNA damage and oncogenic activation being some of the best described. The capacity of p53 to control cellular events such as cell cycle progression, DNA repair, and apoptosis, to mention some, has bee...
Autores principales: | Fusée, Leïla T. S., Marín, Mónica, Fåhraeus, Robin, López, Ignacio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072472/ https://www.ncbi.nlm.nih.gov/pubmed/32050651 http://dx.doi.org/10.3390/cancers12020401 |
Ejemplares similares
-
The p53 endoplasmic reticulum stress-response pathway evolved in humans but not in mice via PERK-regulated p53 mRNA structures
por: Fusée, Leila, et al.
Publicado: (2023) -
p53-mediated control of gene expression via mRNA translation during Endoplasmic Reticulum stress
por: López, Ignacio, et al.
Publicado: (2015) -
p53-mediated suppression of BiP triggers BIK-induced apoptosis during prolonged endoplasmic reticulum stress
por: López, Ignacio, et al.
Publicado: (2017) -
p53 mRNA Metabolism Links with the DNA Damage Response
por: Vadivel Gnanasundram, Sivakumar, et al.
Publicado: (2021) -
MDM2’s dual mRNA binding domains co-ordinate its oncogenic and tumour suppressor activities
por: Gnanasundram, Sivakumar Vadivel, et al.
Publicado: (2020)