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Donor Heme Oxygenase-1 Promoter Gene Polymorphism Predicts Survival after Unrelated Bone Marrow Transplantation for High-Risk Patients
Heme oxygenase-1 (HO-1), an intracellular enzyme that catalyzes the degradation of heme into biliverdin, free iron, and carbon monoxide, exerts anti-inflammatory and cytoprotective effects against endothelial cell injury. The HO-1 promoter gene has one important single-nucleotide polymorphism (SNP)...
Autores principales: | Horio, Tomohiro, Morishita, Eriko, Mizuno, Shohei, Uchino, Kaori, Hanamura, Ichiro, Espinoza, J. Luis, Morishima, Yasuo, Kodera, Yoshihisa, Onizuka, Makoto, Kashiwase, Koichi, Fukuda, Takahiro, Doki, Noriko, Miyamura, Koichi, Mori, Takehiko, Nakao, Shinji, Takami, Akiyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072481/ https://www.ncbi.nlm.nih.gov/pubmed/32059452 http://dx.doi.org/10.3390/cancers12020424 |
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