A20 Promotes Ripoptosome Formation and TNF-Induced Apoptosis via cIAPs Regulation and NIK Stabilization in Keratinocytes

The ubiquitin-editing protein A20 (TNFAIP3) is a known key player in the regulation of immune responses in many organs. Genome-wide associated studies (GWASs) have linked A20 with a number of inflammatory and autoimmune disorders, including psoriasis. Here, we identified a previously unrecognized ro...

Descripción completa

Detalles Bibliográficos
Autores principales: Feoktistova, Maria, Makarov, Roman, Brenji, Sihem, Schneider, Anne T., Hooiveld, Guido J., Luedde, Tom, Leverkus, Martin, Yazdi, Amir S., Panayotova-Dimitrova, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072579/
https://www.ncbi.nlm.nih.gov/pubmed/32028675
http://dx.doi.org/10.3390/cells9020351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072579/
https://www.ncbi.nlm.nih.gov/pubmed/32028675
http://dx.doi.org/10.3390/cells9020351

Ejemplares similares