Cargando…

Identification of Novel Rare ABCC1 Transporter Mutations in Tumor Biopsies of Cancer Patients

The efficiency of chemotherapy drugs can be affected by ATP-binding cassette (ABC) transporter expression or by their mutation status. Multidrug resistance is linked with ABC transporter overexpression. In the present study, we performed rare mutation analyses for 12 ABC transporters related to drug...

Descripción completa

Detalles Bibliográficos
Autores principales: Kadioglu, Onat, Saeed, Mohamed, Munder, Markus, Spuller, Andreas, Greten, Henry Johannes, Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072590/
https://www.ncbi.nlm.nih.gov/pubmed/31991926
http://dx.doi.org/10.3390/cells9020299