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Current Advances in Allosteric Modulation of Muscarinic Receptors

Allosteric modulators are ligands that bind to a site on the receptor that is spatially separated from the orthosteric binding site for the endogenous neurotransmitter. Allosteric modulators modulate the binding affinity, potency, and efficacy of orthosteric ligands. Muscarinic acetylcholine recepto...

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Detalles Bibliográficos
Autores principales:	Jakubik, Jan, El-Fakahany, Esam E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072599/ https://www.ncbi.nlm.nih.gov/pubmed/32085536 http://dx.doi.org/10.3390/biom10020325

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