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Lipid–Saporin Nanoparticles for the Intracellular Delivery of Cytotoxic Protein to Overcome ABC Transporter-Mediated Multidrug Resistance In Vitro and In Vivo

Although the judicious use of anticancer drugs that target one or more receptor tyrosine kinases constitutes an effective strategy to attenuate tumor growth, drug resistance is commonly encountered in cancer patients. The ATP-binding cassette transporters are one of the major contributors to the dev...

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Detalles Bibliográficos
Autores principales: Zhang, Guan-Nan, Gupta, Pranav, Wang, Ming, Barbuti, Anna Maria, Ashby, Charles R., Zhang, Yun-Kai, Zeng, Leli, Xu, Qiaobing, Fan, Ying-Fang, Chen, Zhe-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072609/
https://www.ncbi.nlm.nih.gov/pubmed/32098067
http://dx.doi.org/10.3390/cancers12020498