Cyclin-Dependent Kinase 5 Inhibitor Butyrolactone I Elicits a Partial Agonist Activity of Peroxisome Proliferator-Activated Receptor γ

Adiponectin is an adipocyte-derived cytokine having an insulin-sensitizing activity. During the phenotypic screening of secondary metabolites derived from the marine fungus Aspergillus terreus, a poly cyclin-dependent kinase (CDK) inhibitor butyrolactone I affecting CDK1 and CDK5 was discovered as a...

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Detalles Bibliográficos
Autores principales: Ahn, Sungjin, Jang, Dong Man, Park, Sung Chul, An, Seungchan, Shin, Jongheon, Han, Byung Woo, Noh, Minsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072624/
https://www.ncbi.nlm.nih.gov/pubmed/32054125
http://dx.doi.org/10.3390/biom10020275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072624/
https://www.ncbi.nlm.nih.gov/pubmed/32054125
http://dx.doi.org/10.3390/biom10020275

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