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Effects of Germline CYP2W16 and CYP2B66 Single Nucleotide Polymorphisms on Mitotane Treatment in Adrenocortical Carcinoma: A Multicenter ENSAT Study

Mitotane is the only approved drug for advanced adrenocortical carcinoma (ACC) and no biomarkers are available to predict attainment of therapeutic plasma concentrations and clinical response. Aim of the study was to evaluate the suitability of cytochrome P450(CYP)2W1 and CYP2B6 single nucleotide po...

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Detalles Bibliográficos
Autores principales:	Altieri, Barbara, Sbiera, Silviu, Herterich, Sabine, De Francia, Silvia, Della Casa, Silvia, Calabrese, Anna, Pontecorvi, Alfredo, Quinkler, Marcus, Kienitz, Tina, Mannelli, Massimo, Canu, Letizia, Angelousi, Anna, Chortis, Vasileios, Kroiss, Matthias, Terzolo, Massimo, Fassnacht, Martin, Ronchi, Cristina L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072643/ https://www.ncbi.nlm.nih.gov/pubmed/32033200 http://dx.doi.org/10.3390/cancers12020359

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