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Targeting the Class A Carbapenemase GES-5 via Virtual Screening
The worldwide spread of β-lactamases able to hydrolyze last resort carbapenems contributes to the antibiotic resistance problem and menaces the successful antimicrobial treatment of clinically relevant pathogens. Class A carbapenemases include members of the KPC and GES families. While drugs against...
Autores principales: | Klein, Raphael, Cendron, Laura, Montanari, Martina, Bellio, Pierangelo, Celenza, Giuseppe, Maso, Lorenzo, Tondi, Donatella, Brenk, Ruth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072645/ https://www.ncbi.nlm.nih.gov/pubmed/32075131 http://dx.doi.org/10.3390/biom10020304 |
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