A SOX2 Reporter System Identifies Gastric Cancer Stem-Like Cells Sensitive to Monensin

Gastric cancer remains a serious health burden with few therapeutic options. Therefore, the recognition of cancer stem cells (CSCs) as seeds of the tumorigenic process makes them a prime therapeutic target. Knowing that the transcription factors SOX2 and OCT4 promote stemness, our approach was to is...

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Detalles Bibliográficos
Autores principales: Pádua, Diana, Barros, Rita, Luísa Amaral, Ana, Mesquita, Patrícia, Filipa Freire, Ana, Sousa, Mafalda, Filipe Maia, André, Caiado, Inês, Fernandes, Hugo, Pombinho, António, Filipe Pereira, Carlos, Almeida, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072720/
https://www.ncbi.nlm.nih.gov/pubmed/32093282
http://dx.doi.org/10.3390/cancers12020495

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