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The Cell Cycle Checkpoint System MAST(L)-ENSA/ARPP19-PP2A is Targeted by cAMP/PKA and cGMP/PKG in Anucleate Human Platelets
The cell cycle is controlled by microtubule-associated serine/threonine kinase-like (MASTL), which phosphorylates the cAMP-regulated phosphoproteins 19 (ARPP19) at S62 and 19e/α-endosulfine (ENSA) at S67and converts them into protein phosphatase 2A (PP2A) inhibitors. Based on initial proteomic data,...
Autores principales: | Kumm, Elena J., Pagel, Oliver, Gambaryan, Stepan, Walter, Ulrich, Zahedi, René P., Smolenski, Albert, Jurk, Kerstin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072724/ https://www.ncbi.nlm.nih.gov/pubmed/32085646 http://dx.doi.org/10.3390/cells9020472 |
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