Underestimated Aspect of Mucopolysaccharidosis Pathogenesis: Global Changes in Cellular Processes Revealed by Transcriptomic Studies

Mucopolysaccharidoses (MPS), a group of inherited metabolic disorders caused by deficiency in enzymes involved in degradation of glycosaminoglycans (GAGs), are examples (and models) of monogenic diseases. Accumulation of undegraded GAGs in lysosomes was supposed to be the major cause of MPS symptoms...

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Detalles Bibliográficos
Autores principales: Gaffke, Lidia, Pierzynowska, Karolina, Podlacha, Magdalena, Hoinkis, Dżesika, Rintz, Estera, Brokowska, Joanna, Cyske, Zuzanna, Wegrzyn, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072725/
https://www.ncbi.nlm.nih.gov/pubmed/32054071
http://dx.doi.org/10.3390/ijms21041204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072725/
https://www.ncbi.nlm.nih.gov/pubmed/32054071
http://dx.doi.org/10.3390/ijms21041204

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