Cargando…

Plasma Membrane Transporters as Biomarkers and Molecular Targets in Cholangiocarcinoma

The dismal prognosis of patients with advanced cholangiocarcinoma (CCA) is due, in part, to the extreme resistance of this type of liver cancer to available chemotherapeutic agents. Among the complex mechanisms accounting for CCA chemoresistance are those involving the impairment of drug uptake, whi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marin, Jose J.G., Macias, Rocio I.R., Cives-Losada, Candela, Peleteiro-Vigil, Ana, Herraez, Elisa, Lozano, Elisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072733/ https://www.ncbi.nlm.nih.gov/pubmed/32098199 http://dx.doi.org/10.3390/cells9020498

Ejemplares similares

Molecular Bases of Mechanisms Accounting for Drug Resistance in Gastric Adenocarcinoma
por: Marin, Jose J. G., et al.
Publicado: (2020)

Usefulness of the MRP2 promoter to overcome the chemoresistance of gastrointestinal and liver tumors by enhancing the expression of the drug transporter OATP1B1
por: Herraez, Elisa, et al.
Publicado: (2017)

Mechanisms of Anticancer Drug Resistance in Hepatoblastoma
por: Marin, Jose J. G., et al.
Publicado: (2019)

Novel Pharmacological Options in the Treatment of Cholangiocarcinoma: Mechanisms of Resistance
por: Marin, Jose J. G., et al.
Publicado: (2021)

Role of drug transporters in the sensitivity of acute myeloid leukemia to sorafenib
por: Macias, Rocio I.R., et al.
Publicado: (2018)

Cellular Mechanisms Accounting for the Refractoriness of Colorectal Carcinoma to Pharmacological Treatment
por: Marin, Jose J.G., et al.
Publicado: (2020)

Genetic Heterogeneity of SLC22 Family of Transporters in Drug Disposition
por: Lozano, Elisa, et al.
Publicado: (2018)

Role of the Plasma Membrane Transporter of Organic Cations OCT1 and Its Genetic Variants in Modern Liver Pharmacology
por: Lozano, Elisa, et al.
Publicado: (2013)

Molecular Bases of Drug Resistance in Hepatocellular Carcinoma
por: Marin, Jose J.G., et al.
Publicado: (2020)

The lack of the organic cation transporter OCT1 at the plasma membrane of tumor cells precludes a positive response to sorafenib in patients with hepatocellular carcinoma
por: Geier, Andreas, et al.
Publicado: (2017)

Models for Understanding Resistance to Chemotherapy in Liver Cancer
por: Marin, Jose J. G., et al.
Publicado: (2019)

Expression of Chemoresistance-Associated ABC Proteins in Hepatobiliary, Pancreatic and Gastrointestinal Cancers
por: Marin, Jose J. G., et al.
Publicado: (2022)

Lactation during cholestasis: Role of ABC proteins in bile acid traffic across the mammary gland
por: Blazquez, Alba M. G., et al.
Publicado: (2017)

Impact of Aberrant β-Catenin Pathway on Cholangiocarcinoma Heterogeneity
por: Lozano, Elisa, et al.
Publicado: (2023)

Serum Metabolites as Diagnostic Biomarkers for Cholangiocarcinoma, Hepatocellular Carcinoma, and Primary Sclerosing Cholangitis
por: Banales, Jesus M., et al.
Publicado: (2019)

The promise of precision medicine: how biomarkers are shaping the future of cholangiocarcinoma treatment
por: Macias, Rocio I. R., et al.
Publicado: (2023)

Role of Intracellular Drug Disposition in the Response of Acute Myeloid Leukemia to Cytarabine and Idarubicin Induction Chemotherapy
por: Rodríguez-Macías, Gabriela, et al.
Publicado: (2023)

Cholangiocarcinoma: Biology, Clinical Management, and Pharmacological Perspectives
por: Macias, Rocio I. R.
Publicado: (2014)

Plasma Membrane Transporters in Modern Liver Pharmacology
por: Marin, Jose J. G.
Publicado: (2012)

A Novel Serum Metabolomic Profile for the Differential Diagnosis of Distal Cholangiocarcinoma and Pancreatic Ductal Adenocarcinoma
por: Macias, Rocio I.R., et al.
Publicado: (2020)

The role of reduced intracellular concentrations of active drugs in the lack of response to anticancer chemotherapy
por: Marin, Jose JG, et al.
Publicado: (2014)

Long Non-Coding RNAs as Molecular Biomarkers in Cholangiocarcinoma
por: Wu, Yanhua, et al.
Publicado: (2022)

Patients with Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease Diagnosis
por: Lapitz, Ainhoa, et al.
Publicado: (2020)

Pharmacogenetics of hepatocellular carcinoma and cholangiocarcinoma
por: Alonso-Peña, Marta, et al.
Publicado: (2019)

An Omics Perspective on Molecular Biomarkers for Diagnosis, Prognosis, and Therapeutics of Cholangiocarcinoma
por: Seeree, Pattaya, et al.
Publicado: (2015)

Corrigendum: Long non-coding RNAs as molecular biomarkers in cholangiocarcinoma
por: Wu, Yanhua, et al.
Publicado: (2022)

Locoregional Treatments in Cholangiocarcinoma and Combined Hepatocellular Cholangiocarcinoma
por: Renzulli, Matteo, et al.
Publicado: (2021)

Liver Metastases of Intrahepatic Cholangiocarcinoma: Implications for an Updated Staging System
por: Lamarca, Angela, et al.
Publicado: (2021)

Molecular origin of plasma membrane citrate transporter in human prostate epithelial cells
por: Mazurek, Maciej P, et al.
Publicado: (2010)

Intracellular transport of phosphatidylcholine to the plasma membrane
Publicado: (1985)

Plasma Bile Acid Profiling and Modulation of Secreted Mucin 5AC in Cholangiocarcinoma
por: Danese, Elisa, et al.
Publicado: (2023)

Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis, and prognostication of cholangiocarcinoma
por: Lapitz, Ainhoa, et al.
Publicado: (2023)

Machine Learning Model Comparison in the Screening of Cholangiocarcinoma Using Plasma Bile Acids Profiles
por: Negrini, Davide, et al.
Publicado: (2020)

Impact of Alternative Splicing Variants on Liver Cancer Biology
por: Marin, Jose J. G., et al.
Publicado: (2021)

Next-Generation Biomarkers for Cholangiocarcinoma
por: Rodrigues, Pedro M., et al.
Publicado: (2021)

Molecular Pathogenesis of Cholangiocarcinoma
por: Fava, G., et al.
Publicado: (2012)

Molecular Pathogenesis of Cholangiocarcinoma
por: Labib, Peter L., et al.
Publicado: (2019)

Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium
por: Milenkovic, Ljiljana, et al.
Publicado: (2009)

TGFβ-induced circLTBP2 predicts a poor prognosis in intrahepatic cholangiocarcinoma and mediates gemcitabine resistance by sponging miR-338-3p
por: Louis, Corentin, et al.
Publicado: (2023)

A Rare Clinical Presentation of Cholangiocarcinoma
por: Gravito-Soares, Elisa, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_pgrjh195g88jov25cgtgudlbe5