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Phosphorylation-Dependent Differences in CXCR4-LASP1-AKT1 Interaction between Breast Cancer and Chronic Myeloid Leukemia

The serine/threonine protein kinase AKT1 is a downstream target of the chemokine receptor 4 (CXCR4), and both proteins play a central role in the modulation of diverse cellular processes, including proliferation and cell survival. While in chronic myeloid leukemia (CML) the CXCR4 is downregulated, t...

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Detalles Bibliográficos
Autores principales:	Butt, Elke, Stempfle, Katrin, Lister, Lorenz, Wolf, Felix, Kraft, Marcella, Herrmann, Andreas B., Viciano, Cristina Perpina, Weber, Christian, Hochhaus, Andreas, Ernst, Thomas, Hoffmann, Carsten, Zernecke, Alma, Frietsch, Jochen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072741/ https://www.ncbi.nlm.nih.gov/pubmed/32075106 http://dx.doi.org/10.3390/cells9020444

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