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Protein Expression Profile in Rat Silicosis Model Reveals Upregulation of PTPN2 and Its Inhibitory Effect on Epithelial-Mesenchymal Transition by Dephosphorylation of STAT3

Silicosis is a chronic occupational lung disease caused by long-term inhalation of crystalline silica particulates. We created a rat model that closely approximates the exposure and development of silicosis in humans. Isobaric tags for relative and absolute quantitation (iTRAQ) technologies we used...

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Detalles Bibliográficos
Autores principales: Zhu, Ying, Yao, Jingxin, Duan, Yuxia, Xu, Hong, Cheng, Qiyun, Gao, Xuemin, Li, Shumin, Yang, Fang, Liu, Heliang, Yuan, Juxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072761/
https://www.ncbi.nlm.nih.gov/pubmed/32054021
http://dx.doi.org/10.3390/ijms21041189