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Mitochondrial E3 Ubiquitin Ligase Parkin: Relationships with Other Causal Proteins in Familial Parkinson’s Disease and Its Substrate-Involved Mouse Experimental Models

Parkinson’s disease (PD) is a common neurodegenerative disorder. Recent identification of genes linked to familial forms of PD has revealed that post-translational modifications, such as phosphorylation and ubiquitination of proteins, are key factors in disease pathogenesis. In PD, E3 ubiquitin liga...

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Detalles Bibliográficos
Autores principales:	Torii, Satoru, Kasai, Shuya, Yoshida, Tatsushi, Yasumoto, Ken-ichi, Shimizu, Shigeomi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072767/ https://www.ncbi.nlm.nih.gov/pubmed/32054064 http://dx.doi.org/10.3390/ijms21041202

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