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Mathematical Model of ATM Activation and Chromatin Relaxation by Ionizing Radiation
We propose a comprehensive mathematical model to study the dynamics of ionizing radiation induced Ataxia-telangiectasia mutated (ATM) activation that consists of ATM activation through dual mechanisms: the initiative activation pathway triggered by the DNA damage-induced local chromatin relaxation a...
Autores principales: | Li, Yongfeng, Cucinotta, Francis A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072770/ https://www.ncbi.nlm.nih.gov/pubmed/32059363 http://dx.doi.org/10.3390/ijms21041214 |
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