Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway

Interferon γ (IFN-γ) was shown to be a macrophage activating factor already in 1984. Consistently, inborn errors of IFN-γ immunity underlie Mendelian Susceptibility to Mycobacterial Disease (MSMD). MSMD is characterized by genetic predisposition to disease caused by weakly virulent mycobacterial spe...

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Detalles Bibliográficos
Autores principales: Haake, Kathrin, Neehus, Anna-Lena, Buchegger, Theresa, Kühnel, Mark Philipp, Blank, Patrick, Philipp, Friederike, Oleaga-Quintas, Carmen, Schulz, Ansgar, Grimley, Michael, Goethe, Ralph, Jonigk, Danny, Kalinke, Ulrich, Boisson-Dupuis, Stéphanie, Casanova, Jean-Laurent, Bustamante, Jacinta, Lachmann, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072779/
https://www.ncbi.nlm.nih.gov/pubmed/32093117
http://dx.doi.org/10.3390/cells9020483

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