PIK3R1(W624R) Is an Actionable Mutation in High Grade Serous Ovarian Carcinoma

Identifying cancer drivers and actionable mutations is critical for precision oncology. In epithelial ovarian cancer (EOC) the majority of mutations lack biological or clinical validation. We fully characterized 43 lines of Patient-Derived Xenografts (PDXs) and performed copy number analysis and who...

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Detalles Bibliográficos
Autores principales: D’Ambrosio, Concetta, Erriquez, Jessica, Arigoni, Maddalena, Capellero, Sonia, Mittica, Gloria, Ghisoni, Eleonora, Borella, Fulvio, Katsaros, Dionyssios, Privitera, Silvana, Ribotta, Marisa, Maldi, Elena, Di Nardo, Giovanna, Berrino, Enrico, Venesio, Tiziana, Ponzone, Riccardo, Vaira, Marco, Hall, Douglas, Jimenez-Linan, Mercedes, Paterson, Anna L., Calogero, Raffaele A., Brenton, James D., Valabrega, Giorgio, Di Renzo, Maria Flavia, Olivero, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072782/
https://www.ncbi.nlm.nih.gov/pubmed/32075097
http://dx.doi.org/10.3390/cells9020442

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