In Steatotic Cells, ATP-Citrate Lyase mRNA Is Efficiently Translated through a Cap-Independent Mechanism, Contributing to the Stimulation of De Novo Lipogenesis

Non-alcoholic fatty liver disease (NAFLD) is a chronic disease in which excessive amount of lipids is accumulated as droplets in hepatocytes. Recently, cumulative evidences suggested that a sustained de novo lipogenesis can play an important role in NAFLD. Dysregulated expression of lipogenic genes,...

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Detalles Bibliográficos
Autores principales: Siculella, Luisa, Giannotti, Laura, Testini, Mariangela, Gnoni, Gabriele V., Damiano, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072811/
https://www.ncbi.nlm.nih.gov/pubmed/32054087
http://dx.doi.org/10.3390/ijms21041206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072811/
https://www.ncbi.nlm.nih.gov/pubmed/32054087
http://dx.doi.org/10.3390/ijms21041206

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