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The Crosstalk between Cardiac Lipotoxicity and Mitochondrial Oxidative Stress in the Cardiac Alterations in Diet-Induced Obesity in Rats

The impact of the mitochondria-targeted antioxidant MitoQ was evaluated in the cardiac alterations associated with obesity. Male Wistar rats were fed either a high fat diet (HFD, 35% fat) or a standard diet (CT, 3.5% fat) for 7 weeks and treated with MitoQ (200 µM). The effect of MitoQ (5 nM) in rat...

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Detalles Bibliográficos
Autores principales: Jiménez-González, Sara, Marín-Royo, Gema, Jurado-López, Raquel, Bartolomé, María Visitación, Romero-Miranda, Ana, Luaces, María, Islas, Fabián, Nieto, María Luisa, Martínez-Martínez, Ernesto, Cachofeiro, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072852/
https://www.ncbi.nlm.nih.gov/pubmed/32079154
http://dx.doi.org/10.3390/cells9020451