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IL-21 in Conjunction with Anti-CD40 and IL-4 Constitutes a Potent Polyclonal B Cell Stimulator for Monitoring Antigen-Specific Memory B Cells

Detection of antigen-specific memory B cells for immune monitoring requires their activation, and is commonly accomplished through stimulation with the TLR7/8 agonist R848 and IL-2. To this end, we evaluated whether addition of IL-21 would further enhance this TLR-driven stimulation approach; which...

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Detalles Bibliográficos
Autores principales:	Franke, Fridolin, Kirchenbaum, Greg A., Kuerten, Stefanie, Lehmann, Paul V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072853/ https://www.ncbi.nlm.nih.gov/pubmed/32069813 http://dx.doi.org/10.3390/cells9020433

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