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Chronic Cannabidiol Administration Fails to Diminish Blood Pressure in Rats with Primary and Secondary Hypertension Despite Its Effects on Cardiac and Plasma Endocannabinoid System, Oxidative Stress and Lipid Metabolism

We investigated the influence of cannabidiol (CBD) on blood pressure (BP) and heart rate (HR) in spontaneously (SHR) and deoxycorticosterone (DOCA-salt) hypertensive rats. Hypertension was connected with increases in cardiac and plasma markers of lipid peroxidation in both models, whereas cardiac en...

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Detalles Bibliográficos
Autores principales: Remiszewski, Patryk, Jarocka-Karpowicz, Iwona, Biernacki, Michał, Jastrząb, Anna, Schlicker, Eberhard, Toczek, Marek, Harasim-Symbor, Ewa, Pędzińska-Betiuk, Anna, Malinowska, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072941/
https://www.ncbi.nlm.nih.gov/pubmed/32075117
http://dx.doi.org/10.3390/ijms21041295

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