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Chronic Cannabidiol Administration Fails to Diminish Blood Pressure in Rats with Primary and Secondary Hypertension Despite Its Effects on Cardiac and Plasma Endocannabinoid System, Oxidative Stress and Lipid Metabolism
We investigated the influence of cannabidiol (CBD) on blood pressure (BP) and heart rate (HR) in spontaneously (SHR) and deoxycorticosterone (DOCA-salt) hypertensive rats. Hypertension was connected with increases in cardiac and plasma markers of lipid peroxidation in both models, whereas cardiac en...
Autores principales: | Remiszewski, Patryk, Jarocka-Karpowicz, Iwona, Biernacki, Michał, Jastrząb, Anna, Schlicker, Eberhard, Toczek, Marek, Harasim-Symbor, Ewa, Pędzińska-Betiuk, Anna, Malinowska, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072941/ https://www.ncbi.nlm.nih.gov/pubmed/32075117 http://dx.doi.org/10.3390/ijms21041295 |
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