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Sarcoma Family Kinase-Dependent Pannexin-1 Activation after Cortical Spreading Depression Is Mediated by NR2A-Containing Receptors

Cortical spreading depression (CSD) is a propagating wave of depolarization followed by depression of cortical activity. CSD triggers neuroinflammation via the pannexin-1 (Panx1) channel opening, which may eventually cause migraine headaches. However, the regulatory mechanism of Panx1 is unknown. Th...

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Detalles Bibliográficos
Autores principales: Bu, Fan, Nie, Lingdi, Quinn, John P, Wang, Minyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072958/
https://www.ncbi.nlm.nih.gov/pubmed/32070042
http://dx.doi.org/10.3390/ijms21041269