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Downregulation of S1P Lyase Improves Barrier Function in Human Cerebral Microvascular Endothelial Cells Following an Inflammatory Challenge

Sphingosine 1-phosphate (S1P) is a key bioactive lipid that regulates a myriad of physiological and pathophysiological processes, including endothelial barrier function, vascular tone, vascular inflammation, and angiogenesis. Various S1P receptor subtypes have been suggested to be involved in the re...

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Detalles Bibliográficos
Autores principales:	Stepanovska, Bisera, Lange, Antonia I., Schwalm, Stephanie, Pfeilschifter, Josef, Coldewey, Sina M., Huwiler, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072972/ https://www.ncbi.nlm.nih.gov/pubmed/32069843 http://dx.doi.org/10.3390/ijms21041240

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