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The Rho/Rac Guanine Nucleotide Exchange Factor Vav1 Regulates Hif-1α and Glut-1 Expression and Glucose Uptake in the Brain

Vav1 is a Rho/Rac (Ras-related C3 botulinum toxin substrate) guanine nucleotide exchange factor expressed in hematopoietic and endothelial cells that are involved in a wide range of cellular functions. It is also stabilized under hypoxic conditions when it regulates the accumulation of the transcrip...

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Detalles Bibliográficos
Autores principales: Hong, Jaewoo, Kim, Yurim, Yanpallewar, Sudhirkumar, Lin, P. Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072975/
https://www.ncbi.nlm.nih.gov/pubmed/32079227
http://dx.doi.org/10.3390/ijms21041341

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