Extranodal NK/T-Cell Lymphomas: The Role of Natural Killer Cells and EBV in Lymphomagenesis

Natural killer (NK) cells are lymphocytes involved in innate and adaptive immune functions. They are the presumed cell of origin of distinct hematolymphoid malignancies, including aggressive NK-cell leukemia and extranodal NK/T-cell lymphoma (ENKTL). This review focuses on the role of NK cells and E...

Descripción completa

Detalles Bibliográficos
Autores principales: Saleem, Atif, Natkunam, Yasodha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073055/
https://www.ncbi.nlm.nih.gov/pubmed/32098335
http://dx.doi.org/10.3390/ijms21041501
_version_ 1783506549405122560
author Saleem, Atif
Natkunam, Yasodha
author_facet Saleem, Atif
Natkunam, Yasodha
author_sort Saleem, Atif
collection PubMed
description Natural killer (NK) cells are lymphocytes involved in innate and adaptive immune functions. They are the presumed cell of origin of distinct hematolymphoid malignancies, including aggressive NK-cell leukemia and extranodal NK/T-cell lymphoma (ENKTL). This review focuses on the role of NK cells and Epstein–Barr virus (EBV) in ENKTL pathogenesis.
format Online
Article
Text
id pubmed-7073055
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-70730552020-03-19 Extranodal NK/T-Cell Lymphomas: The Role of Natural Killer Cells and EBV in Lymphomagenesis Saleem, Atif Natkunam, Yasodha Int J Mol Sci Review Natural killer (NK) cells are lymphocytes involved in innate and adaptive immune functions. They are the presumed cell of origin of distinct hematolymphoid malignancies, including aggressive NK-cell leukemia and extranodal NK/T-cell lymphoma (ENKTL). This review focuses on the role of NK cells and Epstein–Barr virus (EBV) in ENKTL pathogenesis. MDPI 2020-02-22 /pmc/articles/PMC7073055/ /pubmed/32098335 http://dx.doi.org/10.3390/ijms21041501 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Saleem, Atif
Natkunam, Yasodha
Extranodal NK/T-Cell Lymphomas: The Role of Natural Killer Cells and EBV in Lymphomagenesis
title Extranodal NK/T-Cell Lymphomas: The Role of Natural Killer Cells and EBV in Lymphomagenesis
title_full Extranodal NK/T-Cell Lymphomas: The Role of Natural Killer Cells and EBV in Lymphomagenesis
title_fullStr Extranodal NK/T-Cell Lymphomas: The Role of Natural Killer Cells and EBV in Lymphomagenesis
title_full_unstemmed Extranodal NK/T-Cell Lymphomas: The Role of Natural Killer Cells and EBV in Lymphomagenesis
title_short Extranodal NK/T-Cell Lymphomas: The Role of Natural Killer Cells and EBV in Lymphomagenesis
title_sort extranodal nk/t-cell lymphomas: the role of natural killer cells and ebv in lymphomagenesis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073055/
https://www.ncbi.nlm.nih.gov/pubmed/32098335
http://dx.doi.org/10.3390/ijms21041501
work_keys_str_mv AT saleematif extranodalnktcelllymphomastheroleofnaturalkillercellsandebvinlymphomagenesis
AT natkunamyasodha extranodalnktcelllymphomastheroleofnaturalkillercellsandebvinlymphomagenesis

Ejemplares similares