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The ER Unfolded Protein Response Effector, ATF6, Reduces Cardiac Fibrosis and Decreases Activation of Cardiac Fibroblasts
Activating transcription factor-6 α (ATF6) is one of the three main sensors and effectors of the endoplasmic reticulum (ER) stress response and, as such, it is critical for protecting the heart and other tissues from a variety of environmental insults and disease states. In the heart, ATF6 has been...
Autores principales: | Stauffer, Winston T., Blackwood, Erik A., Azizi, Khalid, Kaufman, Randal J., Glembotski, Christopher C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073073/ https://www.ncbi.nlm.nih.gov/pubmed/32085622 http://dx.doi.org/10.3390/ijms21041373 |
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