The Surprising Effect of Phenformin on Cutaneous Darkening and Characterization of Its Underlying Mechanism by a Forward Chemical Genetics Approach

Melanin in the epidermis is known to ultimately regulate human skin pigmentation. Recently, we exploited a phenotypic-based screening system composed of ex vivo human skin cultures to search for effective materials to regulate skin pigmentation. Since a previous study reported the potent inhibitory...

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Detalles Bibliográficos
Autores principales: Takano, Kei, Hachiya, Akira, Murase, Daiki, Kawasaki, Akiko, Uda, Hirokazu, Kasamatsu, Shinya, Sugai, Yoshiya, Takahashi, Yoshito, Hase, Tadashi, Ohuchi, Atsushi, Suzuki, Tamio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073119/
https://www.ncbi.nlm.nih.gov/pubmed/32093380
http://dx.doi.org/10.3390/ijms21041451

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