Role of VEGFs/VEGFR-1 Signaling and Its Inhibition in Modulating Tumor Invasion: Experimental Evidence in Different Metastatic Cancer Models

The vascular endothelial growth factor (VEGF) family members, VEGF-A, placenta growth factor (PlGF), and to a lesser extent VEGF-B, play an essential role in tumor-associated angiogenesis, tissue infiltration, and metastasis formation. Although VEGF-A can activate both VEGFR-1 and VEGFR-2 membrane r...

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Detalles Bibliográficos
Autores principales: Ceci, Claudia, Atzori, Maria Grazia, Lacal, Pedro Miguel, Graziani, Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073125/
https://www.ncbi.nlm.nih.gov/pubmed/32085654
http://dx.doi.org/10.3390/ijms21041388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073125/
https://www.ncbi.nlm.nih.gov/pubmed/32085654
http://dx.doi.org/10.3390/ijms21041388

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