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Influence of Exercise Training on Skeletal Muscle Insulin Resistance in Aging: Spotlight on Muscle Ceramides
Intramuscular lipid accumulation has been associated with insulin resistance (IR), aging, diabetes, dyslipidemia, and obesity. A substantial body of evidence has implicated ceramides, a sphingolipid intermediate, as potent antagonists of insulin action that drive insulin resistance. Indeed, genetic...
Autores principales: | Reidy, Paul T., Mahmassani, Ziad S., McKenzie, Alec I., Petrocelli, Jonathan J., Summers, Scott A., Drummond, Micah J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073171/ https://www.ncbi.nlm.nih.gov/pubmed/32098447 http://dx.doi.org/10.3390/ijms21041514 |
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