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Tissue Distribution of the Readthrough Isoform of AQP4 Reveals a Dual Role of AQP4ex Limited to CNS
Translational readthrough (TRT) of aquaporin-4 (AQP4) has remarkably expanded the importance of this new post-transcriptional mechanism, as well as the regulation potential of AQP4. The TRT isoform of AQP4, named AQP4ex, is central for both AQP4 polarization and water channel activity in the central...
Autores principales: | Palazzo, Claudia, Abbrescia, Pasqua, Valente, Onofrio, Nicchia, Grazia Paola, Banitalebi, Shervin, Amiry-Moghaddam, Mahmood, Trojano, Maria, Frigeri, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073200/ https://www.ncbi.nlm.nih.gov/pubmed/32102323 http://dx.doi.org/10.3390/ijms21041531 |
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