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Tissue Distribution of the Readthrough Isoform of AQP4 Reveals a Dual Role of AQP4ex Limited to CNS

Translational readthrough (TRT) of aquaporin-4 (AQP4) has remarkably expanded the importance of this new post-transcriptional mechanism, as well as the regulation potential of AQP4. The TRT isoform of AQP4, named AQP4ex, is central for both AQP4 polarization and water channel activity in the central...

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Detalles Bibliográficos
Autores principales: Palazzo, Claudia, Abbrescia, Pasqua, Valente, Onofrio, Nicchia, Grazia Paola, Banitalebi, Shervin, Amiry-Moghaddam, Mahmood, Trojano, Maria, Frigeri, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073200/
https://www.ncbi.nlm.nih.gov/pubmed/32102323
http://dx.doi.org/10.3390/ijms21041531

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